• br Clinical characteristics Brugada syndrome is

  2019-05-07

  

  Clinical characteristics Brugada syndrome is more common in Southeast Asia, including Japan, with an estimated prevalence of 12 in 10,000 individuals, compared with Western countries where the estimated prevalence is 1 to 5 in 10,000 individuals. However, the incidence of early repolarization syn

• br Discussion The presence of metastases at

  2019-05-07

  

  Discussion The presence of metastases at the time of diagnosis is a significant prognostic factor in osteosarcoma [14]. Skeletal metastases at time of presentations appears to carry a worse prognosis than pulmonary metastases [15]. Furthermore, the chance of survival can be improved by surgical r

• br Conflict of interest br

  2019-05-07

  

  Conflict of interest Acknowledgment Introduction The majority of clot embolisms associated with atrial fibrillation (AF) are from the left atrial appendage (LAA). Before cardioversion or catheter ablation, clot formation needs to be ruled out traditionally using transesophageal echocardiogr

• It is important to know whether

  2019-05-07

  

  It is important to know whether pilsicainide can be used as a therapeutic agent for LQT2 patients; and if so, we should determine the types of LQT2 mutation carriers to whom pilsicainide could be administered. As shown in Fig. 8, we examined the effects of pilsicainide on two mutant hERG proteins, G

• Introduction Friedenstein was the first

  2019-05-06

  

  Introduction Friedenstein was the first person to describe the isolation of clonogenic, proliferating fibroblastic MSCs from rat bone marrow (BM). And they showed that colony-forming unit fibroblasts (CFU-Fs) derived stromal order zip can serve as feeder layers for the culture of heamatopoietic ste

• This patient s shortest R R interval on ECG was

  2019-05-06

  

  This patient\'s shortest R–R interval on ECG was about 200ms (300bpm), which indicated high risk of sudden cardiac death. The patient underwent catheter ablation. ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias [1], which include accessory pathway-mediated arr

• br Short case report A year old

  2019-05-06

  

  Short case report A 65-year-old man with persistent AF underwent multi-detector computed tomography (CT) before catheter ablation. An anomalous muscular band connecting the posterior side of the left atrial roof and the right edge of fossa ovalis in the left atrium was detected (Fig. 1). During

• This Ca overload activates the

  2019-05-06

  

  This Ca2+ overload activates the forward mode of the Na+/Ca+ exchanger (NCX), increases the transient inward current (Iti), and induces ventricular arrhythmias due to delayed after depolarizations (DADs). Subtypes of CPVT Several subtypes of CPVT have been reported (Table 1). The most common typ

• In humans the two primary

  2019-05-06

  

  In humans, the two primary bile acids CA and CDCA make up approximately 70%–80% of the total bile hexokinase regulation pool. DCA is the major secondary bile acid, which may account for approximately 20% of the total bile acid pool. Among all bile acid species, the secondary bile acid LCA is highly

• br The translational pipeline in

  2019-05-06

  

  The translational pipeline in biomedicine (from bench to bedside) focused the attention of the global research pmpa on delivery of results to patients. The notion was rapidly accepted, as shown by the training of researchers in translational approaches, the establishment of translational research

• The diagnostic infrastructure in the public sector relies

  2019-05-06

  

  The diagnostic infrastructure in the public sector relies mainly on sputum smear microscopy that cannot detect drug resistance. It is only when patients fail to get better on standard treatment, or have recurrence of tuberculosis, that they get screened for MDR-TB, resulting in morbidity, continued

• br Drug resistant tuberculosis threatens

  2019-05-06

  

  Drug-resistant tuberculosis threatens to undermine advances in tuberculosis control worldwide. Multidrug-resistant tuberculosis (MDRTB), defined as resistance to isoniazid and rifampicin, requires treatment for up to 24 months with expensive diagnostics and second-line drugs. Fewer than 15% of pat

• br Discussion The present meta

  2019-05-05

  

  Discussion The present meta-analysis of randomized trials demonstrated that treatment with AAMs is associated with an increase in non-cardiac and all-cause mortality as compared to non-arrhythmic therapy or control group. There was no significant reduction in cardiac or arrhythmic mortality betwe

• Do ponto de vista da

  2019-05-05

  

  Do ponto de vista da insurgência, order H 89 resposta governamental se encaixava perfeitamente à leitura política sustentada por Guzmán. O “presidente” pregava que a ação senderista explicitaria a violência estatal, constrangendo o campesinato a se levantar contra o Estado e em última análise, tomar

• Second the growing population which was traditionally depend

  2019-05-05

  

  Second, the growing population, which was traditionally dependent on millet, barley, and maize as staples in their diet, has developed an unsustainable appetite for rice, which puts pressure on rice production. As a result, growing numbers of dams are being constructed in rivers in the Himalayas to

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