• br Case Report The patient was an year old Asian

  2018-11-06

  

  Case Report The patient was an 83-year-old Asian man (68.7 kg, 165 cm; body mass index: 25.2 kg/m2) with multiple comorbidities including diabetes mellitus, chronic heart failure, and a left inguinal hernia. He had undergone Bassini hernioplasty 10 years previously. He had sustained a left intert

• To determine the time required for accurate viability assess

  2018-11-06

  

  To determine the time required for accurate viability assessment, approximately 1000 A. caninum eggs were transferred into 1.5mL centrifuge tubes, suspended in 1mL Phosphate Buffer Saline (PBS), and heat-inactivated on a heating block for 30min at 80°C. Tubes were centrifuged at 800× for 3min, and t

• This is further confirmed by

  2018-11-06

  

  This is further confirmed by the very significant decrease in MDA level by Trévo™ and its positive effect on catalase and SOD. In the present study, the decreased level of GSH has been associated with elevations in the levels of end products (MDA) of lipid peroxidation in acetaminophen control. The

• Introduction The transcription factor Nanog was

  2018-11-06

  

  Introduction The transcription factor Nanog was identified based on its ability to support embryonic stem cell (ESC) self-renewal in the absence of leukemia inhibitory factor (LIF) (Chambers et al., 2003). Further studies demonstrated that Nanog helps to maintain pluripotency in ESCs by promoting O

• Direct genetic reprogramming of postnatal

  2018-11-06

  

  Direct genetic reprogramming of postnatal primary cells by forced expression of key developmental transcription factors has emerged as an alternative to in vitro differentiation of PSCs. This strategy has been used successfully to produce functional cells, including neurons, hepatocyte-like cells an

• A whole genome transcriptome analysis

  2018-11-06

  

  A whole genome transcriptome analysis was carried out to clarify the mechanisms of the cell type specific cytotoxicity of HDAC inhibition on the abnormal cells. The transcriptome analysis revealed the HDAC inhibitor responsive genes in the normal and abnormal cells. The genes with altered levels in

• Here we report that Dll counteracts

  2018-11-06

  

  Here we report that Dll4 counteracts the proliferation of murine HPCs such as Lin−Sca+c-Kit+ (LSK) cells, by keeping a higher fraction of cells in the G0 state. This event was correlated with a downmodulation of some key cyp450 inducers genes transcription such as D-CYCLINS. Furthermore, Dll4 limit

• br Our group has utilized human fetal

  2018-11-06

  

  Our group has utilized human fetal hearts and a lineage-tracing, Isl1–cre knock-in hESC line as tools to study the developmental programs during human cardiogenesis and to examine the paracrine signaling mechanisms involved in self-renewal (Qyang et al., 2007) and lineage specification (Lui et al.

• Host pathogen interaction is a balancing

  2018-11-06

  

  Host-pathogen interaction is a balancing act as viruses evolved to have strategies to evade the host defense system. HCV NS3, core and NS5A proteins are involved in immune evasion by modulating specific and innate immune pathways (Basu et al., 2001; Horner and Gale, 2013). NS3 protease can effective

• Host pathogen interaction is a balancing

  2018-11-06

  

  Host-pathogen interaction is a balancing act as viruses evolved to have strategies to evade the host defense system. HCV NS3, core and NS5A proteins are involved in immune evasion by modulating specific and innate immune pathways (Basu et al., 2001; Horner and Gale, 2013). NS3 protease can effective

• br Materials and methods br Verification and authentication

  2018-11-06

  

  Materials and methods Verification and authentication Karyotyping and PCR-RFLP analysis were performed at Reproductive & Genetic Hospital of CITIC-Xiangya. Twenty metaphase cells were observed and all had a normal karyotype of 46, XX. The results of PCR-RFLP assay confirmed a homozygous deleti

• Metabolic therapy has become trendy in

  2018-11-06

  

  Metabolic therapy has become trendy in attenuating the side effects of glioma treatment (Schwartz et al., 2015; Zuccoli et al., 2010; Seyfried et al., 2015). This type of therapy is designed to disrupt tumor microenvironment, while enhancing the health and vitality of normal cells. It has been demon

• br Materials and methods br Results br Discussion The presen

  2018-11-06

  

  Materials and methods Results Discussion The present study characterises the early effects and safety profile of hMSC therapy in a large animal model of ALI. After 4h of treatment, we have demonstrated that hMSC reduced tissue NF-κB, an important transcription factor that mediates Epoxomici

• To unveil the underlying molecular mechanisms by which

  2018-11-05

  

  To unveil the underlying molecular mechanisms by which miR-375 promotes hASC osteogenesis, we conducted a microarray analysis 7 days after osteoinduction. According to the microarray profiles, the osteogenesis-associated genes RUNX2 (ratio = 1.6431) and ALP (ratio = 1.6367) were upregulated, and DEP

• In this article we discuss the invariant differential

  2018-11-05

  

  In this article we discuss the invariant differential production spectra measured for φ-mesons in p + Pb collisions at 5.02 TeV at different centralities. Nuclear modification factors for φ-mesons in p + Pb interactions have been determined using the obtained data. Reconstruction of the φ-meson d

15597 records 1024/1040 page Previous Next First page 上5页 10211022102310241025 下5页 Last page