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Regarding JNK phosphorylation levels were
2018-10-29
Regarding JNK, phosphorylation levels were either moderately (for JNK 1) or significantly increased (for JNK 2/3) at 5μM SB203580 compared to DMSO controls; these effects were further pronounced at 30μM (Figs. 5 A–B, schema in Figs. 6 C–D). This suggests a concentration-dependent activation of JNK b
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br Materials and methods br
2018-10-29
Materials and methods Results and discussion Conclusion India has enormous varieties of underutilized fruits that vary in appearance and organoleptic features as well as presence of varieties of bioactive compounds. The delicious sweet fruits as well as the seeds of M. hexandra (Roxb.) Duba
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One group has recently identified bone marrow BM residing ve
2018-10-29
One group has recently identified bone marrow (BM)-residing very small embryonic-like stem cells (VSELs) in both human and mouse as a putative nonembryonic source for PSCs (Drukała et al., 2012; Kucia et al., 2006b; Wojakowski et al., 2009; Zuba-Surma et al., 2011). Mouse VSELs have been characteriz
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br Sources of chick stem cells br Applications and
2018-10-26
Sources of chick stem cells Applications and technologies related to chick stem cells Conclusions Conflict of interest Acknowledgments The authors\' work was supported by the Medical Research Council (MRC) and a Ph.D. scholarship from the programme “Strategic Scholarships for Frontier
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As stem cells are increasingly recognized
2018-10-26
As stem CX5461 cost are increasingly recognized for their regenerative properties in clinical applications, the use of NEHUCB-CD34+ cells would be considered a promising and novel therapeutic approach to overcome the economic and social burden of wound-related treatment. CD133 is a cell surface glyc
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A subset of human BMSCs appears to coincide with
2018-10-26
A subset of human BMSCs appears to coincide with a perisinusoidal population of clonogenic stromal 5-fluorocytosine noted for the expression of CD146, CD105, and ALP (Sacchetti et al., 2007). When cultured as non-differentiated cells, loaded onto an osteoconductive scaffold, and then transplanted i
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The reporter lines allowed us to observe in real
2018-10-26
The reporter lines allowed us to observe in real time that colonies with greater than 300 simvastin displayed slightly higher expression levels of the reporter at the colonies’ outermost few cell layers (Fig. 1A, F, fluorescence profiles across colonies shown in Supplementary Fig. 2M). This is in a
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br Introduction The human gallbladder mainly
2018-10-26
Introduction The human gallbladder mainly functions to concentrate and store bile, and like anatomically close-by organs—the liver and the pancreas—is derived from the foregut endoderm during embryonic development (Spence et al., 2009). The extrahepatic biliary tree (comprising extrahepatic bile
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A question arising from this
2018-10-26
A question arising from this work is whether development sets the stage for the early pathophysiological abnormalities in HD and whether we can identify candidate pathways or genes that will restore neuronal homeostasis and protect striatal MSNs halting disease progression. We believe the black and
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SOX is an essential factor in the maintenance
2018-10-26
SOX2 is an essential factor in the maintenance of both human and murine pluripotency; however, it is upregulated, along with other pluripotency factors, in murine PGCs but not hPGCs. In this study we have clarified the mechanism of its repression in the hPGC-derived TCam-2 SEM the full report and s
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Below we highlight what has been preserved and what is
2018-10-26
Below, we highlight what has been preserved and what is new in the 2016 ISSCR Guidelines for Stem Cell Research and Clinical Translation. We also provide a window into our deliberations and describe key elements of the process from which these revised guidelines emerged. Specific recommendations emb
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Previous studies including one in normal human fibroblasts
2018-10-26
Previous studies, including one in normal human fibroblasts, have demonstrated that HR activity is virtually absent during G1 phase, increases sharply in S phase, and begins to decrease by G2/M, whereas NHEJ activity occurs throughout the cytotoxicity (Mao et al., 2008; Saleh-Gohari and Helleday, 20
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gp120 One of the versions of this EOS is
2018-10-26
One of the versions of this EOS is shown in Fig. 1. The cathode has bracket-shaped cross-section. Nanocarbon emitting coating is deposited onto its inner surface. The anode in the form of two thin tungsten wires is placed inside the cathode box. Full axial length of the system may substantially exce
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The goal of this contribution is to
2018-10-26
The goal of this contribution is to fill the existing gap in the structural studies. In the first stage, we have focused our attention on examining the features of the temperature evolution of the structure of the high-temperature phase of solid (1–x)Pb(Fe2/3W1/3O3)–(x)PbTiO3 solutions in the MPB re
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To verify the paradox within the longitudinal
2018-10-26
To verify the paradox within the longitudinal data, I estimate a linear probability model that relies on a comprehensive set of individual and contextual controls to study the conditional differences in birth outcomes between immigrants and natives. Formally, I consider the following model:where the
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