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Today recent technological advances have
2018-10-30
Today, recent technological advances have dramatically improved the prospect of applying broadly the concept of precision medicine. Large-scale databases, omics technologies, cellular assays, epigenetics, informatics as well as imaging technologies converge towards optimum disease prevention, diagno
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br Limitations Though the use of organ or
2018-10-30
Limitations Though the use of organ- or tissue-on-a-chip devices shows a great deal of promise for future applications, it is important to remember that these are relatively new technologies and require further advancements prior to widespread use. It is first necessary to characterize these devi
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The baseline characteristics of both groups were almost
2018-10-29
The baseline characteristics of both groups were almost comparable (Table 1.). The vRVR rates and the SVR12 rates calculated per each intention-to-treat (ITT) population and for those who completed the full protocol (PP) in each group are presented in (Table 2). The vRVR rates showed no statistica
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The CS SVM classifier can
2018-10-29
The CS-SVM classifier can select a small subset of stage II and III patients who can specifically benefit from 5-FU/oxaliplatin chemotherapy. Patients identified as high CS-SVM benefited significantly from chemotherapy in the training cohort (DFS, 0.001; OS, 0.0003; Fig. 5). In contrast, low CS-SVM
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Value of the data br Data
2018-10-29
Value of the data Data, experimental design, materials and methods Acknowledgments This work was financially supported by the grant sponsors: Shenzhen Municipal Committee of Science and Technology Innovation (Grant number: JC201105190969A) and the National Public Sector (AQSIQ) Special Funds
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br Introduction Learning the relationship between threatenin
2018-10-29
Introduction Learning the relationship between threatening events and the cues that predict the onset of those events is an adaptive process that allows an individual to anticipate and minimize exposure to danger (Ohman and Mineka, 2001). Failure to regulate fear purchase ApexPrep DNA Plasmid Min
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The N is a negative component
2018-10-29
The N170 is a negative component that peaks approximately 170ms post stimulus onset. N170 amplitudes are maximal in occipitotemporal regions, with source localisation studies showing that the N170 indexes activity in the superior temporal sulcus and fusiform gyrus (Sadeh et al., 2010). The N170 refl
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Introduction Thienopyrimidines comprise a thiophene ring fus
2018-10-29
Introduction Thienopyrimidines comprise a thiophene ring fused with the pyrimidine moiety similar to the imidazole moiety in purines [1]. Thienopyrimidines in general have become an interesting structural element in development of pharmaceutical compounds [2,3], and have among others been evaluate
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br Discussion The microscopic space between implant and abut
2018-10-29
Discussion The microscopic space between implant and abutment (microgap) facilitates the infiltration of fluids and Dorsomorphin from tissue fluids and saliva, facilitating bacterial invasion and proliferation [4–6], even in patients with good oral hygiene [1,12,20,22,23]. The bacterial contamina
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Although most clinical studies have
2018-10-29
Although most clinical studies have reported a positive impact of platform switching on crestal bone stability, yet the data have still been controversial and inconclusive & up to date the literature still lacks providing clinical evidence about the true influence of platform switching on preserving
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br Methodology A case study approach was
2018-10-29
Methodology A case study approach was implemented to provide an in-depth analysis of the BIM-based neurokinin 1 receptor analysis and energy performance of buildings. This approach is supported (Naoum, 2007), which states that “case studies are used when a researcher intends to support his/her ar
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Conducting prospective randomized trials is difficult due to
2018-10-29
Conducting prospective, randomized trials is difficult due to the limited number of cases. Therefore, a single standard treatment is not available for thyroid lymphoma. Common treatment regimens are derived from the treatment of extranodal lymphomas. Thyroidectomy and radiotherapy are effective for
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br mtDNA mutation in human cancers Several
2018-10-29
mtDNA mutation in human cancers Several authors have evaluated not only the quantitative change in mtDNA copy number, but also the qualitative mtDNA D-loop mutations in human cancers. D-loop mutations, including the D310 region, have been reported in prostate cancer, head and neck cancer, lung ca
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The patient s postoperative course was uneventful Fig
2018-10-29
The patient\'s postoperative course was uneventful. Fig. 5 shows the patient\'s postoperative radiography. By 6 months postoperatively, the patient\'s pain score fell from 5–6 to 1–2 (based on the VAS) and the numbness and weakness improved (the muscle power increased from 4 to 5). Nineteen months p
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Fig shows the Cryptosporidium oocysts
2018-10-29
Fig. 2 shows the Cryptosporidium oocysts\' mean, minimum, and maximum counts in water samples from Approved, Restricted, and Prohibited zones in Hillsborough River, for the two rain events. On average, the level of bruton\'s tyrosine kinase was highest in the Restricted zone, followed by the Approv
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