• br Materials and methods br Results In

  2021-07-09

  

  Materials and methods Results In the leaves of the studied varieties, one to three nucleoli per nucleus were observed (Fig. 1a), except for the variety Bastardo were a maximum of two nucleoli per nucleus were detected. In the root-tip cells, most of the varieties presented one to three nucleo

• Our results indicate a deregulation of DNA methylation machi

  2021-07-09

  

  Our results indicate a deregulation of DNA methylation machinery during seed development in apomixis. Since DRM2 is targeted loci through an RNA-directed DNA methylation (RdDM) pathway involving 24-nt siRNAs (Stroud et al., 2014, Law and Jacobsen, 2010) and differentially expressed between apomict a

• For example nM MTX markedly stimulates

  2021-07-09

  

  For example, 200nM MTX markedly stimulates the differentiation of the monocytic U937 Tianeptine sodium [39], but only 10nM MTX is sufficient for the inhibition of clonogenicity in the ALL and APL cell lines [22]. Furthermore, an even lower concentration of MTX (2nM) selectively induces the expressi

• Some limitations to our study should be noted First the

  2021-07-09

  

  Some limitations to our study should be noted. First, the sample size of our study was limited. As DDR2 mutations are rare in lung SCC, it is possible that the power of our study was insufficient to detect potential associated factors. Second, a significant proportion of the 271 sequenced patients h

• FLAG tag br Materials and methods br Results The frequency o

  2021-07-09

  

  Materials and methods Results The frequency of hypermethylation of RARbeta, RASSF1A, FHIT, GSTP1, MGMT, VHL and DAPK in patients with primary LSCC was assessed in both the tumor tissue samples and macroscopically and histologically normal mucosa from distant sites of the surgical specimen, FLA

• The cysteinyl leukotrienes cysLTs LTC LTD and LTE are increa

  2021-07-09

  

  The cysteinyl leukotrienes (cysLTs) LTC, LTD, and LTE are increased in the airways of asthmatic subjects, with the ability to induce bronchoconstriction, vascular permeability, and mucus secretion., , , , CysLTs are well established as mediators of allergic rhinitis and asthma on the basis of the e

• Previous studies revealed the expression of the CCR receptor

  2021-07-09

  

  Previous studies revealed the expression of the CCR3 receptor in neurons and its neuroprotective function using mice lacking CCR3 expression (Wainwright et al., 2009). The regulation of CCR3 receptor expression in the microglia and astrocytes was shown in neurological disorders and has been demonstr

• We also identified a role for the transcription factor p

  2021-07-09

  

  We also identified a role for the transcription factor p53 in the regulation of the Crm1 promoter. p53 can activate or repress the transcription of target genes. While activation generally occurs through binding of p53 to its consensus binding site in the promoter region of target genes, for example

• Survival analysis has been widely used in medical

  2021-07-09

  

  Survival analysis has been widely used in medical science, economics, finance, and social science, among others. In many studies, survival data have primary outcomes or responses that are subject to censoring. The Cox model [7], [8] is the most commonly used regression model for survival data, and t

• As mentioned previously dopamine plays a

  2021-07-09

  

  As mentioned previously, dopamine plays a crucial role in reducing prefrontal cortical suppression to the amygdala (Rosenkranz and Grace, 2001) and prefrontal cortex mediated amygdala supression has recently been associated with vagal regulation of HRV (Sakaki et al., 2016). In addition, evidence ha

• The genetic basis of resistance to dieldrin has been

  2021-07-09

  

  The genetic basis of resistance to dieldrin has been described for several insect species as a mutation in the transmembrane domain II of the GABA-Cl or rdl (resistance to dieldrin) gene (ffrench-Constant et al., 2004; Bass et al., 2004; Du et al., 2005). A mutation in the GABA-Cl gene was found at

• br Experimental Procedures br Author Contributions

  2021-07-09

  

  Experimental Procedures Author Contributions Acknowledgments Introduction Estrogen-related receptors (ERRα, ERRβ, and ERRγ) are orphan nuclear receptors whose physiological ligands have not yet been identified. Although ERRs are closely related to estrogen receptors (ERs) they do not res

• br Acknowledgements This work was financially supported by

  2021-07-09

  

  Acknowledgements This work was financially supported by Industrial Technology Institute, Sri Lanka through funds received from Sri Lankan Government Treasury (TG13/69). G. D. Liyanaarachchi received postgraduate research scholarship grant from National Science Foundation Sri Lanka (NSF/SCH/2017/0

• CYP contributes to the metabolism

  2021-07-09

  

  CYP450 contributes to the metabolism of more than 90% of currently available drugs (Shapiro and Shear, 2002). Currently, CYP1A is the most studied xenobiotic-metabolizing isoform in fish and is often used as a biomarker for early effects of pollutants in aquatic organisms (Havelkova et al., 2007). T

• Next we evaluated whether DPP inhibitor suppressed

  2021-07-08

  

  Next, we evaluated whether DPP-4 inhibitor suppressed osteoclast formation by downregulating LPS-induced RANKL expression in stromal cells; DPP-4 inhibitor did not inhibit LPS-induced RANKL expression. Furthermore, we evaluated the effect of DPP-4 on LPS-induced RANKL expression in stromal cells, bu

15494 records 597/1033 page Previous Next First page 上5页 596597598599600 下5页 Last page