• We have expanded these studies by doing EEG

  2022-06-22

  

  We have expanded these studies by doing EEG recording in the ET-1 model. Using this technique, we demonstrated that activation of either the ETA 121 4 or the ETB receptor induces electrical seizures. ET-1 induced electrical seizures occurred in the presence of either the ETA receptor antagonist or t

• BS-181 receptor br Conclusion We have demonstrated that ETB

  2022-06-22

  

  Conclusion We have demonstrated that ETB receptors negatively regulate the expression of AT1 receptors in renal proximal tubule BS-181 receptor from WKY rats but not in SHRs. Short-term activation of the ETB receptor increases AT1 receptor phosphorylation in WKY cells but decreases it in SHR cell

• Immunohistochemical evaluation of gastric cancer tumor sampl

  2022-06-22

  

  Immunohistochemical evaluation of gastric cancer tumor samples revealed that 57.8% (59/101) were positive for GLI1, and 71.3% (72/101) stained positive for SHH [27]. Overexpression of SHH and GLI1 protein were significantly associated with larger tumor size, tumor aggressiveness, and less differenti

• br Direct effect of HDACs

  2022-06-22

  

  Direct effect of HDACs on contractile function by deacetylating cytoskeletal and contractile proteins Role of HDACs in electropathology by transcriptional reprogramming Next to deacetylation of α-tubulin by HDAC6 in experimental and human AF, there is also evidence for transcriptional reprogra

• br Material and methods br Results br Discussion In vitro

  2022-06-22

  

  Material and methods Results Discussion In vitro testing is necessary to study DAA activity and putative RASs. Compared to enzymatic assays and replicons, HCV infectious culture systems reflect the full viral life cycle and previous results in these systems reflected clinical data.[13], [14

• In this new therapeutic era nucleic acid

  2022-06-22

  

  In this new therapeutic era, nucleic VO-Ohpic trihydrate amplification tests (NAATs) remain critically useful. NAATs are recommended to detect HCV RNA in blood following initial serologic diagnosis of HCV infection, to distinguish between spontaneous resolution and progression to chronic infection

• TMC120 receptor The biological function of NPRA is demonstra

  2022-06-22

  

  The biological function of NPRA is demonstrated primarily through the ANP/BNP-dependent GC catalytic activity of the receptor and the production of cGMP, which is regulated by several factors, including hormones, growth factors, physiological milieu, and the ligand itself [26,34,[36], [37], [38], [3

• In insects structural cuticular proteins CPs

  2022-06-21

  

  In insects, structural cuticular proteins (CPs) play important roles in determining the diverse physical properties of the cuticle, depending on developmental stages, as well as different body regions, as a result of interactions with other CPs and the structural biopolymer chitin [4]. Many studies

• Resolving the molecular details of glyco proteome variation

  2022-06-21

  

  Resolving the molecular details of (glyco)proteome variation in different tissues and organs of the human body is critical for the understanding of human biology and disease [59]. Glycoproteomic analysis of disease-related tissues and cells has provided valuable information to identify promising tar

• br Author s contributions br

  2022-06-21

  

  Author's contributions Conflict of interest Acknowledgements This work was supported in part by a grant from Department of Biotechnology (DBT), Government of India (Sanction Order No.: BT/563/NE/U-Excel/2016). MC, PDG and SKM acknowledge the Ministry of Human Resource and Development (MHRD)

• Yeast two hybrid screening studies have provided the

  2022-06-21

  

  Yeast two-hybrid screening studies have provided the foundation for countless investigations of protein-protein interactions [[141], [142], [143]]. To identify additional hepatic proteins similar to GKRP that are implicated in GCK regulation, a group of researchers conducted a two-hybrid study using

• Until now various reports have demonstrated

  2022-06-21

  

  Until now, various reports have demonstrated the therapeutic potential of enzyme-resistant forms of GIP in experimental diabetic animal models , , . In essence, structural modifications performed at the Tyr residue in GIP generate analogues that are completely resistant to the actions of DPP-IV and

• br Materials and methods br Results br Discussion

  2022-06-21

  

  Materials and methods Results Discussion The global pandemic of T2DM has mandated a search for new types of therapeutic agent and several long-acting analogs of naturally occurring incretins, particularly derivatives of GLP-1, have already been adopted in clinical practice [29]. This study

• Galactosidase Gal EC is an enzyme exoglycosidase and

  2022-06-21

  

  α-Galactosidase (α-Gal, EC 3.2.1.22) is an enzyme exoglycosidase, and the main role of this enzyme is the enzymolysis of α-galactoside. After this hydrolysis, galactosylation of cyclodextrins by the α-galactosidase occurs, thus forming α-galactosyl-cyclodextrin. This branched CD is easy to dissolve

• br Materials and methods br Results

  2022-06-21

  

  Materials and methods Results Discussion Zn2+ is an extremely abundant transition metal in the synaptic vesicles of hippocampal glutamatergic mossy fibers and remains a key factor in the modulation of neuronal plasticity (Assaf and Chung, 1984). Disruption of Zn2+ homeostasis is associated

15493 records 399/1033 page Previous Next First page 上5页 396397398399400 下5页 Last page