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The basis for the protonation of chitosan
2023-08-26

The basis for the protonation of chitosan is the alkaline primary amino group, which is also the reason for the special properties of chitosan (Guibal, Van Vooren, Dempsey, & Roussy, 2006; Tamer et al., 2017; Yang et al., 2014). Our previous work (Meng et al., 2012) and several other reports (Yan et
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br Concluding Remarks and Future Perspectives Fluorescent an
2023-08-26

Concluding Remarks and Future Perspectives Fluorescent muscarinic receptor antagonists have helped researchers to elucidate antibiotic MOA and off-target interactions, to screen for new antibiotics, to detect antibiotics in the environment, to track antibiotic uptake throughout cells and organism
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br Introduction Quenchbody Q body immunoassay is a novel bio
2023-08-26

Introduction Quenchbody (Q-body) immunoassay is a novel biosensing technology that uses the quenching of fluorescence by intrinsic tryptophan (Trp) residues in antibody variable regions when dye(s) are conjugated to an antibody or antibody fragments in appropriate position, and de-quenching while
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Phytoremediation technology is defined as the use of plants
2023-08-26

Phytoremediation technology is defined as the use of plants to remove contaminants from soils or to render them harmless, and is regarded as a cost-effective, environmental-friendly method for reclaiming soils contaminated by toxic metals (Lasat, 2002, Mahar et al., 2016, Marrugo-Negrete et al., 201
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The G R mutation is located at the
2023-08-26

The G1202R mutation is located at the solvent front of the ALK kinase domain adjacent to the inhibitor's binding pocket. Although barely reported in the setting of crizotinib resistance, it has emerged as the most refractory mutation to both the first- and second-generation ALK inhibitors. The large
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While the mechanisms by which ALDH regulates cardiac respons
2023-08-26

While the mechanisms by which ALDH2 regulates cardiac responses to pathological stress remain unclear, the capillary rarefaction found in pressure-overloaded ALDH2 Tg hearts provides potential clues. Loss of capillary density and diminished endothelial function occur in pathological hypertrophy [46]
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br Hyperadiponectinemia in disease conditions Other evidence
2023-08-25

Hyperadiponectinemia in disease conditions Other evidence indicates that hyperadiponectinemia does not necessarily always imply a healthy outcome. Indeed, a recent study suggested that hyperadiponectinemia occurs in various diseases. Given that the risk for AD and vascular dementia is increased i
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Despite functional studies demonstrating the role of HT in u
2023-08-25

Despite functional studies demonstrating the role of 5-HT in ureteral contractility, the source of endogenous 5-HT in the ureter is unclear. Since 5-HT-containing enterochromaffin cells, which are present in the gastrointestinal tract, could not be found in the ureter (Nocito et al., 2007, Ripoche,
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br Experiment br Results and discussion
2023-08-25

Experiment Results and discussion Conclusion Introduction Tuberculosis (TB) is a chronic specific bacterial infection caused by bacteria of the Mycobacterium tuberculosis [1]. TB remains one of the deadliest diseases in the world. It is the second leading infectious cause of death after
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br Acknowledgement This work was supported by
2023-08-25

Acknowledgement This work was supported by grants from the American Heart Association Scientist Development Grant (SDG) to A. Elmarakby and 1R01EY023315-01 award to M. Al-Shabrawey. Introduction Inflammatory response is the result of a complex interaction between immune Ibandronate sodium an
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Introduction Myasthenia gravis MG is an autoimmune disorder
2023-08-25

Introduction Myasthenia gravis (MG) is an autoimmune disorder characterized by muscle weakness, which is mainly due to autoantibodies reducing the number or function of postsynaptic Crystal Violet receptors (AChRs) [1], [2]. Animal models have been developed to uncover the immunopathogenesis of MG.
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br Identification of the kinase that phosphorylates P c
2023-08-25

Identification of the kinase that phosphorylates P450c17 The first Ser/Thr kinase that phosphorylates P450c17 was identified only recently. Of the 518 kinases in the human ‘kinome’ 278 are Ser/Thr kinases (Manning et al., 2002), but microarrays identified only 145 Ser/Thr kinases in human NCI-H29
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br Autophagy inducers Macroautophagy is often seen as
2023-08-25

Autophagy inducers Macroautophagy is often seen as a cellular process capable of increasing the fitness of EX 527 and overcome resistance to several forms of stress [9], [10]. As discussed above, it has been proposed by several authors that an effective strategy for enhancing sensitivity of canc
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br Materials and methods br Results br
2023-08-25

Materials and methods Results Discussion In the present study, we found that SSTR2, SSTR5, and DA2R proteins are expressed in ACTH-positive SM-164 in healthy canine pituitary glands, with particularly high positive cell ratios in the intermediate lobes. Somatostatin has been reported to in
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Since obesity appears to impact leptin and adiponectin level
2023-08-25

Since obesity appears to impact leptin and adiponectin levels in opposite manners, several studies have suggested that the serum adiponectin/leptin ratio may be a key parameter in indicating the relative risk of postmenopausal breast cancer (Ollberding et al, 2013, Cleary et al, 2009). Therapeutic s
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